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Indication and Usage

Daily administration of Pulmozyme® (dornase alfa) Inhalation Solution along with standard therapies is indicated in the management of cystic fibrosis patients to improve lung function. In patients with a forced vital capacity (volume of air exhaled with maximum effort and speed) greater than or equal to 40% of predicted, daily administration of Pulmozyme has also been shown to reduce the risk of respiratory tract infections requiring the administration of injectable antibiotics.

In our pivotal study, safety and efficacy of daily administration has not been studied in patients beyond 12 months.

Important Safety Information

  • Pulmozyme should not be used in patients who are allergic to any of its ingredients. Pulmozyme should be used along with standard therapies for cystic fibrosis.
  • When starting Pulmozyme therapy, patients may experience change in or loss of their voice, discomfort in the throat, chest pain, red watery eyes, rash, dizziness, fever, or runny nose.
  • These side effects are usually mild and short-lived.

For further information, please see the Pulmozyme full Prescribing Information. If you have questions, please discuss them with your CF healthcare team.

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Taking Pulmozyme

Taking Pulmozyme

Visit CF Living
This online community is a place for CF patients and caregivers to get advice, share stories and learn about others fighting this disease.

Every day matters.

Even when symptoms aren't present, cystic fibrosis is still present. That's why taking Pulmozyme every day, along with other standard therapies, is so important.

Pulmozyme may be an essential part in your fight against cystic fibrosis (CF).

Pulmozyme works uniquely among CF medicines. It targets extracellular DNA to help keep mucus thin and loose, and goes straight to work in your lungs, where it is needed most. In those with mild to moderate CF*, Pulmozyme may be an essential part in the fight against CF, as it may help improve lung function and reduce the risk of respiratory tract infection. For more information on how Pulmozyme works,
click here.

Pulmozyme Study

When starting Pulmozyme therapy, patients may experience change in or loss of voice, discomfort in the throat, chest pain, red watery eyes, rash, dizziness, fever, or runny nose. These side effects are usually mild and short-lived.

* Patients had an FVC ≥40% predicted. FVC stands for forced vital capacity, a test that shows how well the lungs work. To do the test, patients usually take the deepest breath they can. Then they exhale into a sensor for as long as they can. The amount of air they exhale is their FVC score.

Find effective ways to make time for treatment.

Finding the time and place to take your treatments, including Pulmozyme, can feel difficult. No one is perfect. But establishing and sticking to a routine that fits your lifestyle can help you stay in control. Here are some tips to consider that might help you work treatment time into your lifestyle.

  • Create a routine that fits your day-to-day needs
  • Try reminders, like notes or alarms
  • Put your CF stuff where it can be seen and easily accessed

Looking for more ways to make your or your child's Pulmozyme treatment time more interesting? Visit CFLiving.com for advice on living with CF, tips and suggestions for fitting treatment into daily life and more. As always, be sure to talk to your doctor and CF Care Team about any questions you may have.